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Biological brain of a man? No scientist can look at a human brain and definitively tell you if the DNA has a y-chromosome or not. Scientists have found some trends, but nothing that can identify the sex of a single brain. Think of it like this. If I told you a day in Albany, NY had a high of 65 degrees F, you could not tell me what month the day was in. You’d have an inkling. After all some months are warmer than others on average. But any of the 12 months in Albany have had days that were 65 degrees F. So there are trends. We can say these months average 26 degrees and these average 78, but you’ll never be able to say with 100% accuracy in what month a particular 65 degree day fell.